Ozempic vs Wegovy: UK Comparison
Ozempic and Wegovy both contain semaglutide, but they're approved for different purposes in the UK. This guide explains the key differences in dosing, cost, availability, and which might be appropriate for your situation.
Ozempic is approved for type 2 diabetes with weight loss as a secondary benefit. Wegovy is specifically approved for weight management and offers higher doses. Both contain semaglutide and work the same way, but have different eligibility criteria and costs in the UK.
Head-to-Head Comparison
| Feature | Ozempic | Wegovy |
|---|---|---|
| Active Ingredient | Semaglutide | Semaglutide |
| UK Approved For | Type 2 Diabetes | Weight Management |
| Maximum Dose | 1mg weekly (2mg available) | 2.4mg weekly |
| Average Weight Loss | ~12% | ~15% |
| NHS Available | Yes (for diabetes) | Limited (specialist services) |
| Private Cost | £70-150/month | £150-250/month |
| Supply Status | Occasional shortages | Frequent shortages |
| Administration | Weekly injection | Weekly injection |
Key Differences Explained
Ozempic is licensed in the UK specifically for type 2 diabetes. Any weight loss is considered a beneficial side effect.
Wegovy is licensed specifically for chronic weight management in adults with BMI ≥30 (or ≥27 with weight-related conditions).
Ozempic is typically dosed at 0.25mg, 0.5mg, or 1mg weekly. A 2mg dose exists but is less commonly prescribed.
Wegovy titrates up to 2.4mg weekly over 16-20 weeks, providing a higher maximum dose for weight management.
Ozempic is more widely available and generally cheaper privately (£70-150/month). Available on NHS for diabetes patients.
Wegovy costs more (£150-250/month privately) and has more restricted NHS access through specialist weight management services.
Ozempic has experienced supply issues but is generally more available than Wegovy in the UK.
Wegovy has faced significant supply constraints since its UK launch, with intermittent availability.
Stay Updated on Semaglutide UK
Get notified about availability changes, price updates, and new research. Plus receive our free UK medication guide when it launches.
Which Might Be Right for You?
- You have type 2 diabetes
- You want to manage blood sugar with weight loss benefits
- You prefer a lower-cost option
- Better availability is important to you
- Weight loss is your primary goal
- You don't have type 2 diabetes
- You meet BMI criteria (≥30 or ≥27 with conditions)
- You want the maximum approved dose for weight loss
Important Note
This information is for general guidance only. The choice between Ozempic and Wegovy should be made with a qualified healthcare professional who can assess your individual circumstances, medical history, and eligibility.
Side Effects Comparison
Since both medications contain semaglutide, they share similar side effect profiles. The most common side effects are gastrointestinal:
Nausea
Very Common
Diarrhoea
Common
Vomiting
Common
Constipation
Common
Side effects are typically most pronounced during dose escalation and tend to improve over time. Because Wegovy uses higher doses, some people may experience more intense side effects initially.
Frequently Asked Questions
Related Guides
References & Sources
- NICE. Semaglutide for managing overweight and obesity. Technology appraisal guidance [TA875]. 2023.
- Electronic Medicines Compendium (EMC). Ozempic Summary of Product Characteristics.
- Electronic Medicines Compendium (EMC). Wegovy Summary of Product Characteristics.
- Wilding JPH, et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity. N Engl J Med. 2021.
Medical Disclaimer
This comparison is provided for educational purposes only and should not be used to make treatment decisions. Both Ozempic and Wegovy are prescription medications that require assessment by a qualified healthcare professional. Individual results, eligibility, and suitability vary. Always consult your GP or prescriber before starting, stopping, or switching medications.
Last updated: December 2025
Stay Updated on Semaglutide Availability
Get notified about availability changes, price updates, and new research. Plus receive our free UK medication guide when it launches.